Enclomiphene is used to raise serum total testosterone levels while maintaining sperm counts in the normal range in men with secondary hypogonadism. In 2015 the drug manufacturer received a Complete Response Letter from the U.S. Food and Drug Administration (FDA) for its New Drug Application for enclomiphene, which informed them that the application for the drug could not be approved in its present form.
Enclomiphene is available under the following different brand names: Androxal.
Common side effects of Enclomiphene include:
- Increased Sex Drive
- Mood Swings
Testosterone Replacement Therapy (TRT) shuts down your body’s own production of testosterone and replaces it with synthetic testosterone that is typically injected, which results in testicular shrinkage, infertility, and dependence. However, a newer, cutting-edge approach is testosterone restoration, using oral medications to restore your body’s own natural production of testosterone without these adverse effects.1
Selective Estrogen Receptor Modulators (SERMs) act as estrogen antagonists—they block estrogen from binding to the estrogen receptor in the brain, at the hypothalamus, and the pituitary gland.
So when the brain thinks that it’s not getting enough estrogen, it stimulates the production of the hormones luteinizing hormone (LH) and Follicle Stimulating Hormone (FSH), which increases the testis’s production of testosterone and sperm, respectively. This cleverly stimulates your body into producing more of its own natural testosterone!
Possible Side Effects
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