GDF-8 is designed to inhibit naturally occurring myostatin. Myostatin is an important protein that works to prevent the growth and development of muscle cells. GDF-8 by binding myostatin so that it cannot be activated, which prevents it from binding to it’s own receptors. These receptors normally function to switch off muscle growth when myostatin is bound but because the binding is blocked by GDF-8 then muscle growth can continue unrestricted.
Increased chance of tendon rupture, heart failure due to inflamed cardiac muscle, and rhabdomyolysis, a breakdown of muscle fibers that often leads to kidney failure.
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