HGH is a hormone that’s naturally produced by the pituitary gland in our body, and as implied by its name, it’s the hormone that’s responsible for the regeneration and growth of cells. In addition to increasing bone density and muscle mass, HGH plays a critical role in maintaining the health of tissues, including the ones found in vital organs such as the heart and the brain. HGH binds to specific membrane receptors and binding proteins throughout the body. The hormone increases the uptake and incorporation of amino acids into muscle. HGH has acute, transient insulin-like effects that stimulate glucose uptake into muscle and adipose tissue. However, its chronic effects are antagonistic to insulin, leading to fatty acid mobilization, inhibition of glucose uptake, and reduced insulin sensitivity. HGH also has indirect effects mediated primarily by insulin-like growth factor-I (IGF-I) produced by the liver, although its mechanism of action is poorly understood.
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