MK-677 | 50mg/ml

20 in stock

  • Batch and lot coded with publicly visible lab reports to ensure quality and transparency.
  • Free of adulterants, excipients and flow agents to ensure purity.
  • Tamper-proof seal to ensure safety in transit.
  • RTF vials are Washed, Depyrogented, and ETO Sterilized.
  • Aliquot injectable vials are fully sterilized and filtered.
Order this product within 11 hours and 04 minutes to receive the product before December 9, 2023

$74.95

Description

Ibutamoren (developmental code names MK-677, MK-0677, ) is a potent, long-acting, orally-active, selective, and non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been shown to increase the secretion of several hormones including GH and insulin-like growth factor 1 (IGF-1) and produces sustained increases in the plasma levels of these hormones without affecting cortisol levels. Ibutamoren has been shown to sustain activation of the GH–IGF-1 axis and to increase lean body mass with no change in total fat mass or visceral fat. It is under investigation as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with a growth hormone deficiency, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising potential therapy for the treatment of frailty in the elderly. As of June 2017, ibutamoren is in the preclinical stage of development for growth hormone deficiency.

Since MK-677 is still an Investigational New Drug, it has not yet been approved to be marketed for consumption by humans in the United States. However, it has been used experimentally by some in the bodybuilding community. MK-677 has the chemical formula C27H36N4O5S and molar mass 528.662 g/mol. The elimination half-life of MK-677 is approximately 4-6 hours, but IGF-1 levels in humans remain elevated at a single oral dose of up to 24 hours.

In a clinical study of 8 food-deprived healthy volunteers, ibutamoren reversed protein loss that could cause muscle wasting. In 123 elderly patients with hip fractures, ibutamoren improved gait speed and muscle strength and reduced the number of falls. These studies have shown that ibutamoren has a great ability to prevent muscle loss and strong anti-catabolic effects. Because of these abilities, ibutamoren is a promising candidate for the treatment of muscle wasting diseases (muscular dystrophy, etc). A performed scientific study showed that both in younger and older people,  MK-677 improved the quality of sleep and increased the REM sleep time phase (rapid eye movement). In addition to scientific research, there have been many reports about the subjective improvement of sleep quality in various internet forums.

DISCLAIMER

LABORATORY RESEARCH USE ONLY. This product should only be handled by qualified, and licensed professionals. The product may not be used as a drug, agricultural or pesticide product, food additive, or household chemical – and may not be misbranded as such. All information on this website is available for educational purposes only. Bodily introduction of any kind into humans and/or animals is strictly forbidden by law.

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Customer Reviews

Based on 5 reviews
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T
Tony

Great Service from . Too early to determine the success of GH Pep but quietly confident it will soon show.,

K
Kurt H

Using a old dropped the product was great, it started working within the first 24 hours, noted side effects water attention and increased appetite, strength increases and improved recovery.

P
Priten

MK-677 requires a good shake before use and unfortunately on receiving the product the dropped was sealed shut with dry mk677 rendering it unusable.
Using a old dropped the product was great, it started working within the first 24 hours, noted side effects water attention and increased appetite, strength increases and improved recovery.

R
R.
Great product!

Products and customer service A+, 2nd to none! Very pleased with every product/ transaction.

R
Randy
So far so good

Good products, good price, good service.

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