P21 is a nootropic peptide targeting improved neurogenesis. In animal studies, P21 has been shown to boost levels of BDNF (brain-derived neurotropic factor), thus promoting neurogenesis (nerve growth) and inhibiting the formantion of Amyloid plaques and Tau proteins seen in Alzheimer’s disease. BDNF has been linked not just to enhanced neurogenesis, but to the down regulation of certain enzymes responsible for tau and amyloid plaque formation in Alzheimer’s brains. P21 has been shown to improve cognition in animal models.
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